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Dr. Harvey Pass
 

Dr. Harvey Pass Speech to Ban Asbestos Act, Washington D.C: "This disease, mesothelioma, is on the run." (3/24/04)

I am proud to be an advocate for patients afflicted with asbestos related cancers, and I am proud to represent a small cadre of intensely devoted physicians, researchers, and nurses who, behind the scenes, with far too little resources are trying to gain insight into the management of this disease.  More...


Malignant Pleural Mesothelioma: Surgical Roles and Novel Therapies (2/7/02)

Dr. Harvey Pass' comprehensive review of the literature on mesothelioma diagnosis and treatment is a must read, for both doctors and patients alike. The article carefully reviews the diagnostic and therapeutic options for patients from the time of initial symptoms onward. It addresses without bias the pros and cons of the various surgical options, with or without chemotherapy and radiation.  More...

Date of Preparation:  March 21, 2003
  * Updated August 23, 2005

 *   *   *    *   *   *   *

CURRICULUM VITAE

Dr. Harvey Pass

Harvey I. Pass M.D.

Professor and Chief, Division of Thoracic Surgery and Thoracic Oncology
Department of Cardiothoracic Surgery
NYU School of Medicine and Comprehensive Cancer Center
530 1st Avenue, 9V
New York, New York 10016
Phone: 212.263.7417

OFFICE ADDRESS:

NYU School of Medicine and Comprehensive Cancer Center
530 1st Avenue, 9V
New York, New York 10016

PERSONAL DATA:

Birth Date: 12/26/49
Birth Place: Baltimore, Maryland

Age: 51
Married Spouse: Helen A. (Pogrebniak) Pass M.D.
Daughter: Allexandra R.
Son: Eric C.

EDUCATION:

Johns Hopkins University,
Baltimore, Maryland
1967-1970 , B.A.
Duke University Medical School
Durham, North Carolina,
1970-1973, M.D.

TRAINING:

1973-1974

Duke University Medical Center
Straight Surgical Internship

 

1974-1975

Duke University Medical Center
Straight Surgical Residency

  

 

 

1975-1977

United States Public Health Service Hospital
Staten Island, New York
Staff Surgeon

  

 

 

1977-1980

University of Mississippi Medical Center
Senior and Chief Resident
Division of Surgery

  

 

 

1980-1982

Medical University of South Carolina
Senior Residency and Chief Resident
Division of Cardiothoracic Surgery

 

FACULTY

APPOINTMENTS:

1982-1983

Assistant Professor
Medical University of South Carolina
Division of Cardiothoracic Surgery
Charleston, South Carolina

  

 

 

 

1983-1986

Senior Staff Fellow, Thoracic Oncology Section
Surgery Branch

National Cancer Institute/NIH, Bethesda

  

 

 

 

1983 - 1996

Assistant Professor of Surgery
Uniformed Services University of the
Health Sciences
Bethesda, Maryland

  

 

 

PROFESSIONAL

 

 

APPOINTMENTS:

1986 - 1996

Head, Thoracic Oncology Section and Tenured Senior Investigator
Surgery Branch, National Cancer Institute
Bethesda, Maryland

 

MAJOR PROFESSIONAL SOCIETIES:

American Surgical Association
Association of Military Surgeons
Association of Academic Surgeons
Society of Thoracic Surgeons
Society for Surgical Oncology
Fellow of the American College of Surgeons
Southern Thoracic Surgical Association
Society of University Surgeons
Surgical Biology Club III
American College of Chest Physicians
American Association of Thoracic Surgeons
International Mesothelioma Group
International Association for the Study of Lung Cancer
International Early Lung Cancer Action Project
International Working Group on Pulmonary Metastases
American Society of Clinical Oncology
American Association for Cancer Research
Thoracic Surgery Club

LICENSURE
AND BOARD CERTIFICATION:

1974 - National Board of Medical Examiners
1981 - American Board of Surgery
1983 - American Board of Thoracic Surgery
1992 - American Board of Thoracic Surgery (recertified)
2001 - American Board of Thoracic Surgery (recertified)

HONORS/AWARDS:

1967 -

Cum Laude (High School)

1970 -

Alpha Epsilon Delta, Pre Medical Society
Phi Beta Kappa,Johns Hopkins University

1979 -

Mississippi Regional Trauma Award, First Place Winner Annual Meeting of the Mississippi Medical Society

1980 -

Conrad Jobst Award, First Place Winner, Southeast Surgical Congress
"Comparison of External and Internal Cardiac Massage"

1983 -

Conrad Jobst Award, Third Place Winner, Southeast Surgical Congress
"Augmentation of External Cardiac Massage with the Mast Suit"

1984 -

Rowe Foundation Award for outstanding article by an Institution-Based Physician in the Journal of the South Carolina Medical Association, "Radioactive Microspheres: A useful tool in the investigation of myocardial ischemia".

1989 -

President's Award, Southern Thoracic Surgical Association

1991 -

NIH Directors Award

1992 -

Best Doctors in America (Naifeh S and Smith G, eds): Thoracic Oncologic Surgery

1992 -

Best Cancer Specialists in the U.S. Good Housekeeping, October 1992

1995 -

Hufnagle Award for benchwork research performed by a Georgetown General Surgery Resident

1996 -

First Place: Washington Academy of Sciences Award

1999 -

318 Best Cancer Specialists for Women in the U.S. Good Housekeeping, March 1999

2000 -

Presidents Award for Clinical Research, Karmanos Cancer Institute

2001 -

America’s Top Doctors. Castle Connoly’s Guide

2002 -

America’s Top Doctors. Castle Connoly’s Guide

SERVICE:

1. Patient Care: General and Cardiothoracic Surgery, specifically Thoracic Oncology

2. Professional Consultation:

a. Public presentations as an expert in discipline
        Mesothelioma. Defense Research Institute Meeting. New York, NY, 1994

b. Testimony before public bodies:
        Defense of PDT for Lung Cancer: ODAC meeting, FDA, September 1997
        Defense of PDT for Lung Cancer: ODAC meeting, FDA, September 1998

c.. Consulting to public agencies, foundations, professional associations
        Site visit Member for review of the Lung Cancer Study Group, 1986
        Surgical expert and speaker for ALCASE, 1998
        Chairman, Scientific Advisory Board, Mesothelioma Applied Research Foundation (MARF)
        Medical Advisory Board, ALCASE 2000 -

d. Consulting to private enterprises:
        Light Medicine, Inc.
        PDT Inc.
        Pharmacyclics
        Quadra Logics Technologies
        Jansen Pharmacia
        Chiron-Bayer
        Sanofi Pharmaceuticals
        Alfacell
        Battelle
        Xillix
        Lilly

3. Journal/Editorial activity

a. Editorships
        Guest Editor: Adjunctive and Alternative Treatment of Bronchogenic Lung Cancer,
                Chest Surgery Clinics of North America, 1:1, August 1991
        Surgical Editor, Clinical Lung Cancer , 2001-
        Thoracic Surgery Editor, Annals of Surgical Oncology, 2003-

b. Editorial board memberships:

        Journal of the National Cancer Institute, 1990-1994
        Annals of Surgical Oncology, 1993-
        Surgical Oncology, 1993-
        Journal of Surgical Research, 1995-2003
        Clinical Lung Cancer, 1999-
        Current Treatment Options in Oncology, 1999-
        Clinical Cancer Research, 2001-

c. Guest reviewer:

        Cancer Research
        Annals of Thoracic Surgery
        Journal of Thoracic and Cardiovascular Surgery
        Chest
        British Medical Journal
        New England Journal of Medicine
        Journal of Clinical Oncology
        JAMA
        Clinical Cancer Research
        The Cancer Journal of Scientific American
        Cancer
        Clinical Cancer Research
        The Oncologist
        International Journal of Cancer
        Clinical Lung Cancer
        Journal of the National Cancer Institute
        Oncogene

4. Other professionally related service

1997 - Karmanos Cancer Institute Program Leader, Thoracic Oncology
1997 - Karmanos Cancer Institute Clinical Cancer Trials Committee
2002 – Karmanos Cancer Institute Associate Director for Clinical Research
2002 – Karmanos Cancer Institute CEO and President Search Committee

5. National and international boards and committees

a. Positions held in professional associations

        1991 - 1996 NCI representative, American Joint Commission on Cancer
        1991 - 1994 Program Committee, Southern Thoracic Surgical Association

        1991 - 1995 Consultant, American Board of Thoracic Surgeons
        1995 - 1997 Counselor at Large, Southern Thoracic Surgical Association
        1996 - 1998 Young Members Committee, American Association of Thoracic Surgeons
        1998 - 2000 Residents Committee, American Association of Thoracic Surgeons
        1998 - 2000 Thoracic Surgery Foundation for Research and Education, Finance committee
        1998- Executive Committee, International Mesothelioma Interest Group
        1999- Chairman, Scientific Advisory Board, Mesothelioma Applied Research Foundation (MARF)
        2001- Scientific Program Committee: International Association for the Study of Lung Cancer
        2001- Lung Committee, American Society for Clinical Oncology

b. Memberships/offices held in public agencies related to discipline:

        1997 - Michigan Lung Cancer Advisory Committee
        1998 - Michigan Thoracic Society
        1998 - Detroit Academy of Surgery
        1998 - Detroit Surgical Association

6. State and local boards and committees:

1997 - Michigan Lung Cancer Advisory Committee
1997 - Chairman, Detection/Screening of Lung Cancer, Michigan Lung Cancer Advisory Committee

TEACHING:

1. Years at Wayne State: 7.0

2. Years at other colleges/universities

1982 - 1983
        Assistant Professor Medical University of South Carolina
        Division of Cardiothoracic Surgery
        Charleston, South Carolina

1983 - 1996
        Assistant Professor of Surgery
        Uniformed Services University of the Health Sciences Bethesda, Maryland

3. Courses taught at Wayne State in last five years: Cancer Biology

4. Essays/Theses/Dissertations directed: none

5. Course or Curriculum development:

a.  Early Lung Cancer: Strategic Initiatives for Molecular Diagnosis and Treatment, Sommersett Inn, June 15-17, 2000

6. Course materials (unpublished): none

GRANT SUPPORT:

(Pass, H, Principal Investigator)
Olympus America

     

04/01/99 - 10/01/01
$20,000

     

10%

Use of Sputum Induction and Fluorescence Bronchoscopy
for Airway Surveillance and Study of Intermediate Markers
of Neoplasia in Asbestos Exposed Individuals

(Pass, H, Principal Investigator)

10/98 - 10/01

20%

Department of Veterans Affair Merit Review
Detection of SV40 Like Viral DNA in Human Mesothelioma

$93,000/year x 3 years

 

 

(Pass, H, Principal Investigator)
INSPIRE Pharmaceuticals

05/00 – 04/01
$32,593.75

2%

Evaluation of Uridine 5’-Triphosphate Solution
for Inhalation (UTP) as an Adjunct in the Diagnosis
of Lung Cancer by Sputum Cytology

 

 

 

(Pass, H, Principal Investigator)
Eli Lilly and Company

07/99 – 06/02
$3,668/patient

2%

A single-blind randomized phase 3 trial
of MTA plus Cisplatin versus Cisplatin
with malignant pleural mesothelioma

 

 

 

(Kucuk, O, Principal Investigator)
Pass, H, Co-Investigator

01/01 – 06/30/03
$758,959/year

20%

NO1-CN-05022-57
NIH Masters Agreement
Work Statement #68
Zileuton for Bronchial Dysplasia

 

 

 

(Pass, H, Principal Investigator)

01/01 -

Rapid Assessment for Intervention Development (RAID)
NIH Contractual Agreement- approximately $1.4 million
Use of Vac-Tag for Malignant Pleural Mesothelioma

 

 

 

(Schwartz, A.)
Pass, H, Co-Investigator

07/01/00 – 06/30/05
$400,000

5%

NCI
Adenocarcinoma of the Lung in Women

 

 

 

(Pass, H.)

4/01/01-3/31-02

10%

NCI-Early Detection Research Network (Part of UO1)
Gene Arrays and Methylation in Mesothelioma

$100,000

 

 

 

 

(Phillips, M, Principal Investigator)
(Pass, H Consultant)

7/01/01-06/30/03
$700,000

 

NCI-SBIR
Detection of Lung Cancer using Exhaled Gas Determination

 

 

 

 

 

(Pass, H, Principal Investigator)

4/2002-3/2005

 

Veterans Administration, Merit Review
Osteonectin and TIMP1 in Mesothelioma

$363,900

 

 

 

 

(Pass, H, Principal Investigator)

11/2001 – 7/2003

 

KCI Virtual Discovery Grant
Racial Differences in Lung Cancer

$330,000

 

 

 

 

(Wali, A Principal Investigator; Pass H Co-Investigator)

4/2003-3/2006

 

Veterans Administration Merit Review
Intellectin Expression in Mesothelioma

$398,000

 

PROTOCOLS (Principle Investigator)

National Cancer Institute
Intraoperative Radiation Therapy for Thoracic Malignancies, 1984-1986
Phase III Randomized Trial of Neoadjuvant Chemotherapy for NSCLC: 1986-1991
Intraoperative Photodynamic Therapy for Thoracic Malignancies
       Phase I: 1990-1993
       Phase III: 1993-1996
Photodynamic Therapy for Bronchial Obstruction, Phase II: 1987-1996
Immunochemotherapy for Pleural Mesothelioma, Phase II: 1990-1993
Phase I Trial of Isolated Lung Perfusion with Tumor Necrosis Factor: 1994-1996
Phase II Trial of Induction IFN, 5FU, Cisplatin, and Leucovorin for Esophageal Cancer: 1992-1996
Karmanos Cancer Institute
Adriamycin vs Onconase for mesothelioma, ALFACELL:
Early Lung Cancer Detection for Stage I NSCLC resected, CHIRON: BAYER,
MTA-Platinum vs Platinum for mesothelioma, LILLY
Lu-TEX photosensitization for endobronchial disease, IND awarded
Tetrathiomolybdate after resection of Pleural mesothelioma (Investigator initiated)
A Breath Test for Lung Cancer (NIH grant)
Proteomics of Mesothelioma Pleural Effusions (Ciphergen) (Investigator Initiated)
Computerized Tomographic Screening for Lung Cancer (Investigator Initiated, part of International Early Lung Cancer Action Project)


Publications

1. Original observations in refereed journals

 

1. Friedberg, J. S., Mick, R., Stevenson, J., Metz, J., Zhu, T., Buyske, J., Sterman, D. H., Pass, H. I., Glatstein, E., and Hahn, S. M. A phase I study of Foscan-mediated photodynamic therapy and surgery in patients with mesothelioma. Ann.Thorac.Surg., 75: 952-959, 2003.

2. Lonardo, F., Pass, H. I., and Lucas, D. R. Immunohistochemistry Frequently Detects c-Kit Expression in Pulmonary Small Cell Carcinoma and May Help Select Clinical Subsets for a Novel Form of Chemotherapy. Appl.Immunohistochem.Mol.Morphol., 11: 51-55, 2003.

3. Lucas, D. R., Pass, H. I., Madan, S. K., Adsay, N. V., Wali, A., Tabaczka, P., and Lonardo, F. Sarcomatoid mesothelioma and its histological mimics: a comparative immunohistochemical study. Histopathology, 42: 270-279, 2003.

4. Bocchetta, M., Miele, L., Pass, H. I., and Carbone, M. Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells. Oncogene, 22: 81-89, 2003.

5. Pass, H. I. General thoracic surgery and science: it all takes time. Ann.Thorac.Cardiovasc.Surg., 8: 251-252, 2002.

6. Pass, H. I. Pleural mesothelioma in 2002: going somewhere very slowly. J Thorac.Cardiovasc.Surg., 124: 1074-1077, 2002.

7. Friedel, G., Pastorino, U., Ginsberg, R. J., Goldstraw, P., Johnston, M., Pass, H., Putnam, J. B., and Toomes, H. Results of lung metastasectomy from breast cancer: prognostic criteria on the basis of 467 cases of the International Registry of Lung Metastases. Eur.J Cardiothorac.Surg., 22: 335-344, 2002.

8. Pass, H. I. Photodynamic therapy in thoracic surgery. Ann.Thorac.Surg., 73: 2012-2013, 2002.

9. Lechner, J. F., Wang, Y., Siddiq, F., Fugaro, J. M., Wali, A., Lonardo, F., Willey, J. C., Harris, C. C., and Pass, H. I. Human lung cancer cells and tissues partially recapitulate the homeobox gene expression profile of embryonic lung. Lung Cancer, 37: 41-47, 2002.

10. Pass, H. I. Biology of metastatic disease. Semin.Thorac.Cardiovasc.Surg., 14: 10-17, 2002.

11. Bright, R. K., Kimchi, E. T., Shearer, M. H., Kennedy, R. C., and Pass, H. I. SV40 Tag-specific cytotoxic T lymphocytes generated from the peripheral blood of malignant pleural mesothelioma patients. Cancer Immunol.Immunother., 50: 682-690, 2002.

12. Foddis, R., De Rienzo, A., Broccoli, D., Bocchetta, M., Stekala, E., Rizzo, P., Tosolini, A., Grobelny, J. V., Jhanwar, S. C., Pass, H. I., Testa, J. R., and Carbone, M. SV40 infection induces telomerase activity in human mesothelial cells. Oncogene, 21: 1434-1442, 2002.

13. Marom, E. M., Erasmus, J. J., Pass, H. I., and Patz, E. F., Jr. The role of imaging in malignant pleural mesothelioma. Semin.Oncol, 29: 26-35, 2002.

14. Carbone, M. and Pass, H. I. Re: Debate on the link between SV40 and human cancer continues. J Natl.Cancer Inst., 94: 229-230, 2002.

15. Toyooka, S., Pass, H. I., Shivapurkar, N., Fukuyama, Y., Maruyama, R., Toyooka, K. O., Gilcrease, M., Farinas, A., Minna, J. D., and Gazdar, A. F. Aberrant methylation and simian virus 40 tag sequences in malignant mesothelioma. Cancer Res., 61: 5727-5730, 2001.

16. Pass, H. I., Kalemkerian, G., and Bright, R. K. Novel molecular and immunotherapeutic strategies for lung cancer. Chest Surg.Clin N.Am., 11: 189-212, ix, 2001.

17. Imperiale, M. J., Pass, H. I., and Sanda, M. G. Prospects for an SV40 vaccine. Semin.Cancer Biol., 11: 81-85, 2001.

18. Rizzo, P., Bocchetta, M., Powers, A., Foddis, R., Stekala, E., Pass, H. I., and Carbone, M. SV40 and the pathogenesis of mesothelioma. Semin.Cancer Biol., 11: 63-71, 2001.

19. Lechner, J. F., Fugaro, J. M., Wong, Y., Pass, H. I., Harris, C. C., and Belinsky, S. A. Perspective: cell differentiation theory may advance early detection of and therapy for lung cancer. Radiat.Res., 155: 235-238, 2001.

20. Wang, Y., Fugaro, J. M., Siddiq, F., Goparaju, C. M., Lonardo, F., Wali, A., Lechner, J. F., and Pass, H. I. A simple method for generating full length cDNA from low abundance partial genomic clones. BMC.Mol.Biol., 1: 2, 2000.

21. Bocchetta, M., Di, R., I, Powers, A., Fresco, R., Tosolini, A., Testa, J. R., Pass, H. I., Rizzo, P., and Carbone, M. Human mesothelial cells are unusually susceptible to simian virus 40-mediated transformation and asbestos cocarcinogenicity. Proc.Natl.Acad.Sci.U.S.A, 97: 10214-10219, 2000.

22. Marrogi, A., Pass, H. I., Khan, M., Metheny-Barlow, L. J., Harris, C. C., and Gerwin, B. I. Human mesothelioma samples overexpress both cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (NOS2): in vitro antiproliferative effects of a COX-2 inhibitor. Cancer Res., 60: 3696-3700, 2000.

23. Carbone, M., Rizzo, P., and Pass, H. Simian virus 40: the link with human malignant mesothelioma is well established. Anticancer Res., 20: 875-877, 2000.

24. Pass, H. I. Lung cancer surveillance: new technologies and novel strategies. Ann.Surg.Oncol, 7: 171-173, 2000.

25. Shivapurkar, N., Wiethege, T., Wistuba, I. I., Salomon, E., Milchgrub, S., Muller, K. M., Churg, A., Pass, H., and Gazdar, A. F. Presence of simian virus 40 sequences in malignant mesotheliomas and mesothelial cell proliferations. J Cell Biochem., 76: 181-188, 1999.

26. Rizzo, P., Carbone, M., Fisher, S. G., Matker, C., Swinnen, L. J., Powers, A., Di, R., I, Alkan, S., Pass, H. I., and Fisher, R. I. Simian virus 40 is present in most United States human mesotheliomas, but it is rarely present in non-Hodgkin's lymphoma. Chest, 116: 470S-473S, 1999.

27. Pass, H. I., Robinson, B. W., Testa, J. R., and Carbone, M. Emerging translational therapies for mesothelioma. Chest, 116: 455S-460S, 1999.

28. Herscher, L. L., Cook, J. A., Pacelli, R., Pass, H. I., Russo, A., and Mitchell, J. B. Principles of chemoradiation: theoretical and practical considerations. Oncology (Huntingt), 13: 11-22, 1999.

29. Hirvonen, A., Mattson, K., Karjalainen, A., Ollikainen, T., Tammilehto, L., Hovi, T., Vainio, H., Pass, H. I., Di, R., I, Carbone, M., and Linnainmaa, K. Simian virus 40 (SV40)-like DNA sequences not detectable in finnish mesothelioma patients not exposed to SV40-contaminated polio vaccines. Mol.Carcinog., 26: 93-99, 1999.

30. Ohta, Y., Shridhar, V., Bright, R. K., Kalemkerian, G. P., Du, W., Carbone, M., Watanabe, Y., and Pass, H. I. VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours. Br.J Cancer, 81: 54-61, 1999.

31. Shridhar, V., Staub, J., Huntley, B., Cliby, W., Jenkins, R., Pass, H. I., Hartmann, L., and Smith, D. I. A novel region of deletion on chromosome 6q23.3 spanning less than 500 Kb in high grade invasive epithelial ovarian cancer. Oncogene, 18: 3913-3918, 1999.

32. Giuffrida, A., Vianale, G., Di Muzio, M., Pass, H. I., Coletti, A., Birarelli, P., Procopio, A., and Modesti, A. Modulation of integrin expression on mesotheliomas: the role of different histotypes in invasiveness. Int.J Oncol, 15: 437-442, 1999.

33. Carbone, M., Fisher, S., Powers, A., Pass, H. I., and Rizzo, P. New molecular and epidemiological issues in mesothelioma: role of SV40. J Cell Physiol, 180: 167-172, 1999.

34. Ohta, Y., Shridhar, V., Kalemkerian, G. P., Bright, R. K., Watanabe, Y., and Pass, H. I. Thrombospondin-1 expression and clinical implications in malignant pleural mesothelioma. Cancer, 85: 2570-2576, 1999.

35. Scarpa, S., Giuffrida, A., Fazi, M., Coletti, A., Palumbo, C., Pass, H. I., Procopio, A., and Modesti, A. Migration of mesothelioma cells correlates with histotype-specific synthesis of extracellular matrix. Int.J Mol.Med., 4: 67-71, 1999.

36. Xu, L., Flynn, B. J., Ungar, S., Pass, H. I., Linnainmaa, K., Mattson, K., and Gerwin, B. I. Asbestos induction of extended lifespan in normal human mesothelial cells: interindividual susceptibility and SV40 T antigen. Carcinogenesis, 20: 773-783, 1999.

37. Friedel, G., Pastorino, U., Buyse, M., Ginsberg, R. J., Girard, P., Goldstraw, P., Johnston, M., McCormack, P., Pass, H., Putnam, J. B., and Toomes, H. [Resection of lung metastases: long-term results and prognostic analysis based on 5206 cases--the International Registry of Lung Metastases]. Zentralbl.Chir, 124: 96-103, 1999.

38. Watts, A. M., Shearer, M. H., Pass, H. I., Bright, R. K., and Kennedy, R. C. Comparison of simian virus 40 large T antigen recombinant protein and DNA immunization in the induction of protective immunity from experimental pulmonary metastasis. Cancer Immunol.Immunother., 47: 343-351, 1999.

39. DeLaney, T. F., Smith, P. D., Thomas, G. F., Tochner, Z. A., Sindelar, W. F., Pass, H. I., Harrington, F. S., Bonner, R. F., and Mitchell, J. B. A light-diffusing device for intraoperative photodynamic therapy in the peritoneal or pleural cavity. J Clin Laser Med.Surg., 9: 361-366, 1991.

40. Pass, H. I. Pancreatic cancer, gene delivery, and targets: the search for specificity. Ann.Surg.Oncol, 5: 667-669, 1998.

41. Pass, H. I., Donington, J. S., Wu, P., Rizzo, P., Nishimura, M., Kennedy, R., and Carbone, M. Human mesotheliomas contain the simian virus-40 regulatory region and large tumor antigen DNA sequences. J Thorac.Cardiovasc.Surg., 116: 854-859, 1998.

42. Bright, R. K., Shearer, M. H., Pass, H. I., and Kennedy, R. C. Immunotherapy of SV40 induced tumours in mice: a model for vaccine development. Dev.Biol.Stand., 94: 341-353, 1998.

43. Pass, H. I., Mew, D. J., Carbone, M., Donington, J. S., Baserga, R., and Steinberg, S. M. The effect of an antisense expression plasmid to the IGF-1 receptor on hamster mesothelioma proliferation. Dev.Biol.Stand., 94: 321-328, 1998.

44. Carbone, M., Stach, R., Di, R., I, Pass, H. I., and Rizzo, P. Simian virus 40 oncogenesis in hamsters. Dev.Biol.Stand., 94: 273-279, 1998.

45. Pass, H., Rizzo, P., Donington, J., Wu, P., and Carbone, M. Further validation of SV40-like DNA in human pleural mesotheliomas. Dev.Biol.Stand., 94: 143-145, 1998.

46. Rizzo, P., Di, R., I, Stach, R., Mutti, L., Picci, P., Kast, W. M., Pass, H. I., and Carbone, M. Evidence for and implications of SV40-like sequences in human mesotheliomas and osteosarcomas. Dev.Biol.Stand., 94: 33-40, 1998.

47. Temeck, B. K., Wexler, L. H., Steinberg, S. M., McClure, L. L., Horowitz, M. A., and Pass, H. I. Reoperative pulmonary metastasectomy for sarcomatous pediatric histologies. Ann.Thorac.Surg., 66 : 908-912, 1998.

48. Rizzo, P., Di, R., I, Powers, A., Matker, C. M., Zhang, A., Mutti, L., Kast, W. M., Pass, H., and Carbone, M. The detection of simian virus 40 in human tumors by polymerase chain reaction. Monaldi Arch.Chest Dis., 53: 202-210, 1998.

49. Matker, C. M., Rizzo, P., Pass, H. I., Di, R., I, Powers, A., Mutti, L., Kast, W. M., and Carbone, M. The biological activities of simian virus 40 large-T antigen and its possible oncogenic effects in humans. Monaldi Arch.Chest Dis., 53: 193-197, 1998.

50. Sgrignoli, A., Abati, A., Pass, H., Lebovics, R., and Hijazi, Y. Metastatic mesothelioma presenting as a salivary gland neoplasm. Acta Cytol., 42: 818-820, 1998.

51. Pass, H. I. Surgical management of pulmonary metastases. Curr.Opin.Oncol, 10: 146-150, 1998.

52. Shaw, G. L., Falk, R. T., Frame, J. N., Weiffenbach, B., Nesbitt, J. C., Pass, H. I., Caporaso, N. E., Moir, D. T., and Tucker, M. A. Genetic polymorphism of CYP2D6 and lung cancer risk. Cancer Epidemiol.Biomarkers Prev., 7: 215-219, 1998.

53. Williams, K. S., Susla, G., Temeck, B. K., Piscitelli, S. C., and Pass, H. I. Pharmacokinetics of fentanyl during hyperthermic, isolated lung perfusion. South.Med.J, 91: 261-265, 1998.

54. Pass, H. I. and Temeck, B. A. Biology of metastatic disease. Chest Surg.Clin N.Am., 8: 1-11, 1998.

55. Watts, A. M., Shearer, M. H., Pass, H. I., and Kennedy, R. C. Development of an experimental murine pulmonary metastasis model incorporating a viral encoded tumor specific antigen. J Virol.Methods, 69: 93-102, 1997.

56. Pass, H. I., Temeck, B. K., Kranda, K., Steinberg, S. M., and Feuerstein, I. R. Preoperative tumor volume is associated with outcome in malignant pleural mesothelioma. J Thorac.Cardiovasc.Surg., 115: 310-317, 1998.

57. Herscher, L. L., Hahn, S. M., Kroog, G., Pass, H., Temeck, B., Goldspiel, B., Cook, J., Mitchell, J. B., and Liebmann, J. Phase I study of paclitaxel as a radiation sensitizer in the treatment of mesothelioma and non-small-cell lung cancer. J Clin Oncol, 16: 635-641, 1998.

58. Pass, H. I., Temeck, B. K., Kranda, K., Thomas, G., Russo, A., Smith, P., Friauf, W., and Steinberg, S. M. Phase III randomized trial of surgery with or without intraoperative photodynamic therapy and postoperative immunochemotherapy for malignant pleural mesothelioma. Ann.Surg.Oncol, 4: 628-633, 1997.

59. Mawhorter, S., Temeck, B., Chang, R., Pass, H., and Nash, T. Nonsurgical therapy for pulmonary hydatid cyst disease. Chest, 112: 1432-1436, 1997.

60. Carbone, M., Rizzo, P., and Pass, H. I. Simian virus 40, poliovaccines and human tumors: a review of recent developments. Oncogene, 15: 1877-1888, 1997.

61. Wagner, J. R., Merino, M. J., Pass, H. I., Linehan, W. M., and Walther, M. M. Pulmonary infarcts can mimic pulmonary metastases from renal cancer. J Urol., 158: 1688-1690, 1997.

62. Walther, M. M., Yang, J. C., Pass, H. I., Linehan, W. M., and Rosenberg, S. A. Cytoreductive surgery before high dose interleukin-2 based therapy in patients with metastatic renal cell carcinoma. J Urol., 158: 1675-1678, 1997.

63. De Luca, A., Baldi, A., Esposito, V., Howard, C. M., Bagella, L., Rizzo, P., Caputi, M., Pass, H. I., Giordano, G. G., Baldi, F., Carbone, M., and Giordano, A. The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large T-antigen in human mesotheliomas. Nat.Med., 3: 913-916, 1997.

64. Carbone, M., Rizzo, P., Grimley, P. M., Procopio, A., Mew, D. J., Shridhar, V., de Bartolomeis, A., Esposito, V., Giuliano, M. T., Steinberg, S. M., Levine, A. S., Giordano, A., and Pass, H. I. Simian virus-40 large-T antigen binds p53 in human mesotheliomas. Nat.Med., 3: 908-912, 1997.

65. Abati, A., Sanford, J., Fetsch, P., and Pass, H. Detection of aneuploidy in mesothelioma cell lines by fluorescence in situ hybridization (FISH). Diagn.Cytopathol., 16: 375-377, 1997.

66. Pass, H. I., Kranda, K., Temeck, B. K., Feuerstein, I., and Steinberg, S. M. Surgically debulked malignant pleural mesothelioma: results and prognostic factors. Ann.Surg.Oncol, 4: 215-222, 1997.

67. Leschek, E. W., Doppman, J. L., Pass, H. I., and Cutler, G. B., Jr. Localization by venous sampling of occult chorionic gonadotropin-secreting tumor in a boy with mosaic Klinefelter's syndrome and precocious puberty. J Clin Endocrinol.Metab, 81: 3825-3828, 1996.

68. Doppman, J. L., Skarulis, M. C., Chen, C. C., Chang, R., Pass, H. I., Fraker, D. L., Alexander, H. R., Niederle, B., Marx, S. J., Norton, J. A., Wells, S. A., and Spiegel, A. M. Parathyroid adenomas in the aortopulmonary window. Radiology, 201: 456-462, 1996.

69. Temeck, B. K., Koong, S. S., Reynolds, J. C., and Pass, H. I. Somatostatin analogue in the localization and treatment of bronchial carcinoid tumours. Surg.Oncol, 5: 195-200, 1996.

70. Pompetti, F., Rizzo, P., Simon, R. M., Freidlin, B., Mew, D. J., Pass, H. I., Picci, P., Levine, A. S., and Carbone, M. Oncogene alterations in primary, recurrent, and metastatic human bone tumors. J Cell Biochem., 63: 37-50, 1996.

71. Howe, S. R., Pass, H. I., Ethier, S. P., Matthews, W. J., and Walker, C. Presence of an insulin-like growth factor I autocrine loop predicts uterine fibroid responsiveness to tamoxifen. Cancer Res., 56: 4049-4055, 1996.

72. Pass, H. I., Mew, D. J., Carbone, M., Matthews, W. A., Donington, J. S., Baserga, R., Walker, C. L., Resnicoff, M., and Steinberg, S. M. Inhibition of hamster mesothelioma tumorigenesis by an antisense expression plasmid to the insulin-like growth factor-1 receptor. Cancer Res., 56: 4044-4048, 1996.

73. Carbone, M., Rizzo, P., Procopio, A., Giuliano, M., Pass, H. I., Gebhardt, M. C., Mangham, C., Hansen, M., Malkin, D. F., Bushart, G., Pompetti, F., Picci, P., Levine, A. S., Bergsagel, J. D., and Garcea, R. L. SV40-like sequences in human bone tumors. Oncogene, 13: 527-535, 1996.

74. Temeck, B. K., Liebmann, J. E., Theodossiou, C., Steinberg, S. M., Cook, J. A., Metz, D. C., Shawker, T. H., Allegra, C. J., Russo, A., and Pass, H. I. Phase II trial of 5-fluorouracil, leucovorin, interferon-alpha-2a, and cisplatin as neoadjuvant chemotherapy for locally advanced esophageal carcinoma. Cancer, 77: 2432-2439, 1996.

75. Garza, O. T., Abati, A., Sindelar, W. F., Pass, H. I., and Hijazi, Y. M. Cytologic effects of photodynamic therapy in body fluids. Diagn.Cytopathol., 14: 356-361, 1996.

76. Pass, H. I., Mew, D. J., Kranda, K. C., Temeck, B. K., Donington, J. S., and Rosenberg, S. A. Isolated lung perfusion with tumor necrosis factor for pulmonary metastases. Ann.Thorac.Surg., 61: 1609-1617, 1996.

77. Johnson, B. E., Bridges, J. D., Sobczeck, M., Gray, J., Linnoila, R. I., Gazdar, A. F., Hankins, L., Steinberg, S. M., Edison, M., Frame, J. N., Pass, H., Nesbitt, J., Holden, D., Mulshine, J. L., Glatstein, E., and Ihde, D. C. Patients with limited-stage small-cell lung cancer treated with concurrent twice-daily chest radiotherapy and etoposide/cisplatin followed by cyclophosphamide, doxorubicin, and vincristine. J Clin Oncol, 14: 806-813, 1996.

78. Izraeli, S., Mueller, B. U., Ling, A., Temeck, B. K., Lewis, L. L., Chang, R., Shad, A. T., Pass, H. I., and Pizzo, P. A. Role of tissue diagnosis in pulmonary involvement in pediatric human immunodeficiency virus infection. Pediatr.Infect.Dis.J, 15: 112-116, 1996.

79. Shaw, G. L., Gazdar, A. F., Phelps, R., Steinberg, S. M., Linnoila, R. I., Johnson, B. E., Oie, H. K., Russell, E. K., Ghosh, B. C., Pass, H. I., Minna, J. D., Mulshine, J. L., and Ihde, D. C. Correlation of in vitro drug sensitivity testing results with response to chemotherapy and survival: comparison of non-small cell lung cancer and small cell lung cancer. J Cell Biochem.Suppl, 24: 173-185, 1996.

80. Pass, H. I. and Mew, D. J. In vitro and in vivo studies of mesothelioma. J Cell Biochem.Suppl, 24: 142-151, 1996.

81. Pass, H. I., Kennedy, R. C., and Carbone, M. Evidence for and implications of SV40-like sequences in human mesotheliomas. Important Adv.Oncol, 89-108, 1996.

82. Penno, M. B., Askin, F. B., Ma, H., Carbone, M., Vargas, M. P., and Pass, H. I. High CD44 Expression on Human Mesotheliomas Mediates Association with Hyaluronan. Cancer J Sci.Am., 1: 196, 1995.

83. Pass, H. I. and Donington, J. S. Use of photodynamic therapy for the management of pleural malignancies. Semin.Surg.Oncol, 11: 360-367, 1995.

84. Donington, J. S., Mew, D. J., and Pass, H. I. Malignant pleural mesothelioma: newer aspects of carcinogenesis, molecular genetics, and prospects for future therapies. Surg.Oncol, 4: 175-185, 1995.

85. Theodossiou, C., Temeck, B., Vargas, H., Yang, J., Vargas, M., Hahn, S., and Pass, H. Cytomegalovirus enteritis after treatment with 5-fluorouracil, leukovorin, cisplatin, and alpha-interferon. Am.J Gastroenterol., 90: 1174-1176, 1995.

86. Temeck, B. K., Wexler, L. H., Steinberg, S. M., McClure, L. L., Horowitz, M., and Pass, H. I. Metastasectomy for sarcomatous pediatric histologies: results and prognostic factors. Ann.Thorac.Surg., 59: 1385-1389, 1995.

87. Alexander, H. R., Grem, J. L., Hamilton, J. M., Pass, H. I., Hong, M., Fraker, D. L., Steinberg, S. M., McAtee, N., Allegra, C. J., and Johnston, P. G. Thymidylate Synthase Protein Expression. Cancer J Sci.Am., 1: 49, 1995.

88. Pass, H. W., Temeck, B. K., Kranda, K., Steinberg, S. M., and Pass, H. I. A phase II trial investigating primary immunochemotherapy for malignant pleural mesothelioma and the feasibility of adjuvant immunochemotherapy after maximal cytoreduction. Ann.Surg.Oncol, 2: 214-220, 1995.

89. Pass, H. I., Stevens, E. J., Oie, H., Tsokos, M. G., Abati, A. D., Fetsch, P. A., Mew, D. J., Pogrebniak, H. W., and Matthews, W. J. Characteristics of nine newly derived mesothelioma cell lines. Ann.Thorac.Surg., 59: 835-844, 1995.

90. Sekido, Y., Pass, H. I., Bader, S., Mew, D. J., Christman, M. F., Gazdar, A. F., and Minna, J. D. Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer. Cancer Res., 55: 1227-1231, 1995.

91. Temeck, B. K. and Pass, H. I. Esophagopleural fistula: a complication of photodynamic therapy. South.Med.J, 88: 271-274, 1995.

92. Teruya-Feldstein, J., Temeck, B. K., Sloas, M. M., Kingma, D. W., Raffeld, M., Pass, H. I., Mueller, B., and Jaffe, E. S. Pulmonary malignant lymphoma of mucosa-associated lymphoid tissue (MALT) arising in a pediatric HIV-positive patient. Am.J Surg.Pathol., 19: 357-363, 1995.

93. Amin, K. M., Litzky, L. A., Smythe, W. R., Mooney, A. M., Morris, J. M., Mews, D. J., Pass, H. I., Kari, C., Rodeck, U., Rauscher, F. J., III, and . Wilms' tumor 1 susceptibility (WT1) gene products are selectively expressed in malignant mesothelioma. Am.J Pathol., 146: 344-356, 1995.

94. Pass, H. I., Mew, D., Pass, H. A., and Temeck, B. K. The macrophage, TNF, and other cytokines. Chest Surg.Clin N.Am., 5: 73-90, 1995.

95. Yang, J. C., Fraker, D. L., Thom, A. K., Pass, H. I., and Rosenberg, S. A. Isolation perfusion with tumor necrosis factor-alpha, interferon-gamma, and hyperthermia in the treatment of localized and metastatic cancer. Recent Results Cancer Res., 138: 161-166, 1995.

96. Shaw, G. L., Falk, R. T., Deslauriers, J., Frame, J. N., Nesbitt, J. C., Pass, H. I., Issaq, H. J., Hoover, R. N., and Tucker, M. A. Debrisoquine metabolism and lung cancer risk. Cancer Epidemiol.Biomarkers Prev., 4: 41-48, 1995.

97. Williams, K. S., Temeck, B. K., and Pass, H. I. Intrapericardial pheochromocytoma complicated by massive intraoperative hemorrhage. South.Med.J, 87: 1164-1167, 1994.

98. Moskaluk, C. A., Pogrebniak, H. W., Pass, H. I., Gallin, J. I., and Travis, W. D. Surgical pathology of the lung in chronic granulomatous disease. Am.J Clin Pathol., 102: 684-691, 1994.

99. Shilyansky, J., Wilson, W., Temeck, B. K., and Pass, H. I. Pulmonary artery-bronchial fistula during lymphoma treatment. J Thorac.Cardiovasc.Surg., 108: 790-791, 1994.

100. Pass, H. I. and Pogrebniak, H. W. Potential uses of prostaglandin E1 analog for cardiovascular disease. J Thorac.Cardiovasc.Surg., 108: 789-790, 1994.

101. Walsh, T. J., Renshaw, G., Andrews, J., Kwon-Chung, J., Cunnion, R. C., Pass, H. I., Taubenberger, J., Wilson, W., and Pizzo, P. A. Invasive zygomycosis due to Conidiobolus incongruus. Clin Infect.Dis., 19: 423-430, 1994.

102. Zeiger, M. A., Gnarra, J. R., Zbar, B., Linehan, W. M., and Pass, H. I. Loss of heterozygosity on the short arm of chromosome 3 in mesothelioma cell lines and solid tumors. Genes Chromosomes.Cancer, 11: 15-20, 1994.

103. Jensen, S. M., Jones, J. E., Pass, H., Steinberg, S. M., and Linnoila, R. I. Clara cell 10 kDa protein mRNA in normal and atypical regions of human respiratory epithelium. Int.J Cancer, 58: 629-637, 1994.

104. Temeck, B. K., Venzon, D. J., Moskaluk, C. A., and Pass, H. I. Thoracotomy for pulmonary mycoses in non-HIV-immunosuppressed patients. Ann.Thorac.Surg., 58: 333-338, 1994.

105. Pass, H. I. Contemporary approaches in the investigation and treatment of malignant pleural mesothelioma. Chest Surg.Clin N.Am., 4: 497-515, 1994.

106. Pass, H. I. 1987: Delivery of intraoperative radiation therapy after pneumonectomy: experimental observations and early clinical results. Updated in 1994. Ann.Thorac.Surg., 58: 269-270, 1994.

107. Cole, D. J., Ettinghausen, S. E., Pass, H. I., Danforth, D. N., Linehan, M. W., Myers, C. W., Cooper, M. R., and Sindelar, W. F. Postoperative complications in patients receiving suramin therapy. Surgery, 116: 90-95, 1994.

108. Walker, C., Rutten, F., Yuan, X., Pass, H., Mew, D. M., and Everitt, J. Wilms' tumor suppressor gene expression in rat and human mesothelioma. Cancer Res., 54: 3101-3106, 1994.

109. Carbone, M., Pass, H. I., Rizzo, P., Marinetti, M., Di Muzio, M., Mew, D. J., Levine, A. S., and Procopio, A. Simian virus 40-like DNA sequences in human pleural mesothelioma. Oncogene, 9: 1781-1790, 1994.

110. Pogrebniak, H. W., Witt, C. J., Terrill, R., Kranda, K., Travis, W. D., Rosenberg, S. A., and Pass, H. I. Isolated lung perfusion with tumor necrosis factor: a swine model in preparation of human trials. Ann.Thorac.Surg., 57: 1477-1483, 1994.

111. Pass, H. I. Malignant pleural mesothelioma: the thoracic surgeon and gene therapy. Ann.Thorac.Surg., 57: 1383-1384, 1994.

112. Temeck, B. K. and Pass, H. I. A method to facilitate subxiphoid pericardiotomy. Ann.Thorac.Surg., 57: 1015-1017, 1994.

113. Mulshine, J. L., Johnson, B. E., Gazdar, A. F., Shaw, G. L., Kramer, B. S., Mitsudomi, T., Minna, J. D., Pass, H., Phelps, R., Ghosh, B., and . Integrated clinical and basic studies related to circumventing non-small cell lung cancer drug resistance. Lung Cancer, 10 Suppl 1: S73-S81, 1994.

114. Dichek, H. L., Nieman, L. K., Oldfield, E. H., Pass, H. I., Malley, J. D., and Cutler, G. B., Jr. A comparison of the standard high dose dexamethasone suppression test and the overnight 8-mg dexamethasone suppression test for the differential diagnosis of adrenocorticotropin-dependent Cushing's syndrome. J Clin Endocrinol.Metab, 78: 418-422, 1994.

115. Prewitt, T. W., Matthews, W., Chaudhri, G., Pogrebniak, H. W., and Pass, H. I. Tumor necrosis factor induces doxorubicin resistance to lung cancer cells in vitro. J Thorac.Cardiovasc.Surg., 107: 43-49, 1994.

116. Tochner, Z. A., Pass, H. I., Smith, P. D., DeLaney, T. F., Sprague, M., DeLuca, A. M., Harrington, F., Thomas, G. F., Terrill, R., Bacher, J. D., and . Intrathoracic photodynamic therapy: a canine normal tissue tolerance study and early clinical experience. Lasers Surg.Med., 14: 118-123, 1994.

117. Pass, H. I., DeLaney, T. F., Tochner, Z., Smith, P. E., Temeck, B. K., Pogrebniak, H. W., Kranda, K. C., Russo, A., Friauf, W. S., Cole, J. W., and . Intrapleural photodynamic therapy: results of a phase I trial. Ann.Surg.Oncol, 1: 28-37, 1994.

118. Zeiger, M. A., Fraker, D. L., Pass, H. I., Nieman, L. K., Cutler, G. B., Jr., Chrousos, G. P., and Norton, J. A. Effective reversibility of the signs and symptoms of hypercortisolism by bilateral adrenalectomy. Surgery, 114: 1138-1143, 1993.

119. Sheppard, B. C., Temeck, B. K., Taubenberger, J. K., and Pass, H. I. Pulmonary metastatic disease in ameloblastoma. Chest, 104: 1933-1935, 1993.

120. Prewitt, T. W., Lubensky, I. A., Pogrebniak, H. W., and Pass, H. I. Orthotopic implantation of mesothelioma in the pneumonectomized immune-deficient rat: a model for innovative therapies. Int.J Cancer, 55: 877-880, 1993.

121. Shaw, G. L., Gazdar, A. F., Phelps, R., Linnoila, R. I., Ihde, D. C., Johnson, B. E., Oie, H. K., Pass, H. I., Steinberg, S. M., Ghosh, B. C., and . Individualized chemotherapy for patients with non-small cell lung cancer determined by prospective identification of neuroendocrine markers and in vitro drug sensitivity testing. Cancer Res., 53: 5181-5187, 1993.

122. Pass, H. I. and Pogrebniak, H. W. Malignant pleural mesothelioma. Curr.Probl.Surg., 30: 921-1012, 1993.

123. Walther, M. M., Alexander, R. B., Weiss, G. H., Venzon, D., Berman, A., Pass, H. I., Linehan, W. M., and Rosenberg, S. A. Cytoreductive surgery prior to interleukin-2-based therapy in patients with metastatic renal cell carcinoma. Urology, 42: 250-257, 1993.

124. Pogrebniak, H. W., Lubensky, I. A., and Pass, H. I. Differential expression of platelet derived growth factor-beta in malignant mesothelioma: a clue to future therapies? Surg.Oncol, 2: 235-240, 1993.

125. Long, J. P., Choyke, P. L., Shawker, T. A., Robertson, C. A., Pass, H. I., Walther, M. M., and Linehan, W. M. Intraoperative ultrasound in the evaluation of tumor involvement of the inferior vena cava. J Urol., 150: 13-17, 1993.

126. Broers, J. L., Viallet, J., Jensen, S. M., Pass, H., Travis, W. D., Minna, J. D., and Linnoila, R. I. Expression of c-myc in progenitor cells of the bronchopulmonary epithelium and in a large number of non-small cell lung cancers. Am.J Respir.Cell Mol.Biol., 9: 33-43, 1993.

127. Prewitt, T. W. and Pass, H. I. Photodynamic therapy for thoracic cancer: biology and applications. Semin.Thorac.Cardiovasc.Surg., 5: 229-237, 1993.

128. Alexander, H. R., Grem, J. L., Pass, H. I., Hamilton, M., McAtee, N., Fraker, D. L., and Allegra, C. J. Neoadjuvant chemotherapy for locally advanced gastric adenocarcinoma. Oncology (Huntingt), 7: 37-42, 1993.

129. Pogrebniak, H. W., Gallin, J. I., Malech, H. L., Baker, A. R., Moskaluk, C. A., Travis, W. D., and Pass, H. I. Surgical management of pulmonary infections in chronic granulomatous disease of childhood. Ann.Thorac.Surg., 55: 844-849, 1993.

130. Pass, H. I. Photodynamic therapy in oncology: mechanisms and clinical use. J Natl.Cancer Inst., 85: 443-456, 1993.

131. Pogrebniak, H. W. and Pass, H. I. Initial and reoperative pulmonary metastasectomy: indications, technique, and results. Semin.Surg.Oncol, 9: 142-149, 1993.

132. Allende, M., Pizzo, P. A., Horowitz, M., Pass, H. I., and Walsh, T. J. Pulmonary cryptococcosis presenting as metastases in children with sarcomas. Pediatr.Infect.Dis.J, 12: 240-243, 1993.

133. Pogrebniak, H. W., Matthews, W., Black, C., Russo, A., Mitchell, J. B., Smith, P., Roth, J. A., and Pass, H. I. Targetted phototherapy with sensitizer-monoclonal antibody conjugate and light. Surg.Oncol, 2: 31-42, 1993.

134. Zeiger, M. A., Pass, H. I., Doppman, J. D., Nieman, L. K., Chrousos, G. P., Cutler, G. B., Jr., Jensen, R. T., and Norton, J. A. Surgical strategy in the management of non-small cell ectopic adrenocorticotropic hormone syndrome. Surgery, 112: 994-1000, 1992.

135. Medeiros, L. J., Anasti, J., Gardner, K. L., Pass, H. I., and Nieman, L. K. Virilizing adrenal cortical neoplasm arising ectopically in the thorax. J Clin Endocrinol.Metab, 75: 1522-1525, 1992.

136. Pogrebniak, H. W., Merino, M. J., Hahn, S. M., Mitchell, J. B., and Pass, H. I. Spin trap salvage from endotoxemia: the role of cytokine down-regulation. Surgery, 112: 130-139, 1992.

137. Doppman, J. L., Pass, H. I., Nieman, L. K., Miller, D. L., Chang, R., Cutler, G. B., Jr., Chrousos, G. P., Jaffe, G. S., and Norton, J. A. Corticotropin-secreting carcinoid tumors of the thymus: diagnostic unreliability of thymic venous sampling. Radiology, 184: 71-74, 1992.

138. Pogrebniak, H. W., Haas, G., Linehan, W. M., Rosenberg, S. A., and Pass, H. I. Renal cell carcinoma: resection of solitary and multiple metastases. Ann.Thorac.Surg., 54: 33-38, 1992.

139. Pass, H. I. and Pogrebniak, H. Photodynamic therapy for thoracic malignancies. Semin.Surg.Oncol, 8: 217-225, 1992.

140. Pass, H. I., Pogrebniak, H. W., Steinberg, S. M., Mulshine, J., and Minna, J. Randomized trial of neoadjuvant therapy for lung cancer: interim analysis. Ann.Thorac.Surg., 53: 992-998, 1992.

141. Jensen, J. C., Pogrebniak, H. W., Pass, H. I., Buresh, C., Merino, M. J., Kauffman, D., Venzon, D., Langstein, H. N., and Norton, J. A. Role of tumor necrosis factor in oxygen toxicity. J Appl.Physiol, 72: 1902-1907, 1992.

142. Sherry, R. M., Pass, H. I., Rosenberg, S. A., and Yang, J. C. Surgical resection of metastatic renal cell carcinoma and melanoma after response to interleukin-2-based immunotherapy. Cancer, 69 : 1850-1855, 1992.

143. Pogrebniak, H. W., Matthews, W., and Pass, H. I. Alterations in macrophage free radical and tumor necrosis factor production by a potassium channel activator. J Surg.Res., 52: 395-400, 1992.

144. Chang, K., Pai, L. H., Pass, H., Pogrebniak, H. W., Tsao, M. S., Pastan, I., and Willingham, M. C. Monoclonal antibody K1 reacts with epithelial mesothelioma but not with lung adenocarcinoma. Am.J Surg.Pathol., 16: 259-268, 1992.

145. Broers, J. L., Jensen, S. M., Travis, W. D., Pass, H., Whitsett, J. A., Singh, G., Katyal, S. L., Gazdar, A. F., Minna, J. D., and Linnoila, R. I. Expression of surfactant associated protein-A and Clara cell 10 kilodalton mRNA in neoplastic and non-neoplastic human lung tissue as detected by in situ hybridization. Lab Invest, 66: 337-346, 1992.

146. Cook, J. A., Glass, J., Lebovics, R., Bobo, H., Pass, H., DeLaney, T. F., Oldfield, E. H., Mitchell, J. B., Glatstein, E., and Goffman, T. E. Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine. Cancer Res., 52: 719-725, 1992.

147. Doherty, G. M., Doppman, J. L., Miller, D. L., Gee, M. S., Marx, S. J., Spiegel, A. M., Aurbach, G. D., Pass, H. I., Brennan, M. F., and Norton, J. A. Results of a multidisciplinary strategy for management of mediastinal parathyroid adenoma as a cause of persistent primary hyperparathyroidism. Ann.Surg., 215: 101-106, 1992.

148. Feuerstein, I. M., Jicha, D. L., Pass, H. I., Chow, C. K., Chang, R., Ling, A., Hill, S. C., Dwyer, A. J., Travis, W. D., Horowitz, M. E., and . Pulmonary metastases: MR imaging with surgical correlation--a prospective study. Radiology, 182: 123-129, 1992.

149. Kenney, R. T., Kwon-Chung, K. J., Waytes, A. T., Melnick, D. A., Pass, H. I., Merino, M. J., and Gallin, J. I. Successful treatment of systemic Exophiala dermatitidis infection in a patient with chronic granulomatous disease. Clin Infect.Dis., 14: 235-242, 1992.

150. Tochner, Z. A., Pass, H. I., Sindelar, W. F., DeLuca, A. M., Grisell, D. L., Bacher, J. D., and Kinsella, T. J. Long term tolerance of thoracic organs to intraoperative radiotherapy. Int.J Radiat.Oncol Biol.Phys., 22: 65-69, 1992.

151. Pogrebniak, H. W., Prewitt, T. W., Matthews, W. A., and Pass, H. I. Tumor necrosis factor-alpha alters response of lung cancer cells to oxidative stress. J Thorac.Cardiovasc.Surg., 102: 904-907, 1991.

152. Travis, W. D., Kwon-Chung, K. J., Kleiner, D. E., Geber, A., Lawson, W., Pass, H. I., and Henderson, D. Unusual aspects of allergic bronchopulmonary fungal disease: report of two cases due to Curvularia organisms associated with allergic fungal sinusitis. Hum.Pathol., 22: 1240-1248, 1991.

153. Pass, H. I. Bronchial adenoma. Ann.Thorac.Surg., 52: 1201-1203, 1991.

154. Mitsudomi, T., Steinberg, S. M., Oie, H. K., Mulshine, J. L., Phelps, R., Viallet, J., Pass, H., Minna, J. D., and Gazdar, A. F. ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent. Cancer Res., 51: 4999-5002, 1991.

155. Cook, J. A., Pass, H. I., Iype, S. N., Friedman, N., DeGraff, W., Russo, A., and Mitchell, J. B. Cellular glutathione and thiol measurements from surgically resected human lung tumor and normal lung tissue. Cancer Res., 51: 4287-4294, 1991.

156. Pogrebniak, H. W., Roth, J. A., Steinberg, S. M., Rosenberg, S. A., and Pass, H. I. Reoperative pulmonary resection in patients with metastatic soft tissue sarcoma. Ann.Thorac.Surg., 52: 197-203, 1991.

157. Pogrebniak, H. W., Matthews, W., and Pass, H. I. Chemotherapy amplifies production of tumor necrosis factor. Surgery, 110: 231-237, 1991.

158. Travis, W. D., Linnoila, R. I., Tsokos, M. G., Hitchcock, C. L., Cutler, G. B., Jr., Nieman, L., Chrousos, G., Pass, H., and Doppman, J. Neuroendocrine tumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow cytometric study of 35 cases. Am.J Surg.Pathol., 15: 529-553, 1991.

159. Pogrebniak, H., Matthews, W., Mitchell, J., Russo, A., Samuni, A., and Pass, H. Spin trap protection from tumor necrosis factor cytotoxicity. J Surg.Res., 50: 469-474, 1991.

160. Jensen, J. C., Choyke, P. L., Rosenfeld, M., Pass, H. I., Keiser, H., White, B., Travis, W., and Linehan, W. M. A report of familial carotid body tumors and multiple extra-adrenal pheochromocytomas. J Urol., 145: 1040-1042, 1991.

161. Pass, H. I., Evans, S., Matthews, W. A., Perry, R., Venzon, D., Roth, J. A., and Smith, P. Photodynamic therapy of oncogene-transformed cells. J Thorac.Cardiovasc.Surg., 101: 795-799, 1991.

162. Travis, W. D., Hoffman, G. S., Leavitt, R. Y., Pass, H. I., and Fauci, A. S. Surgical pathology of the lung in Wegener's granulomatosis. Review of 87 open lung biopsies from 67 patients. Am.J Surg.Pathol., 15: 315-333, 1991.

163. Jensen, J. C., Pass, H. I., Sindelar, W. F., and Norton, J. A. Recurrent or metastatic disease in select patients with adrenocortical carcinoma. Aggressive resection vs chemotherapy. Arch.Surg., 126: 457-461, 1991.

164. Perry, R. R., Smith, P. D., Evans, S., and Pass, H. I. Intravenous vs intraperitoneal sensitizer: implications for intraperitoneal photodynamic therapy. Photochem.Photobiol., 53: 335-340, 1991.

165. Doppman, J. L., Pass, H. I., Nieman, L. K., Findling, J. W., Dwyer, A. J., Feuerstein, I. M., Ling, A., Travis, W. D., Cutler, G. B., Jr., Chrousos, G. P., and . Detection of ACTH-producing bronchial carcinoid tumors: MR imaging vs CT. AJR Am.J Roentgenol., 156: 39-43, 1991.

166. Pass, H. I. Symposium on thoracic surgical oncology. Ann.Thorac.Surg., 51: 163, 1991.

167. Perry, R. R., Keiser, H. R., Norton, J. A., Wall, R. T., Robertson, C. N., Travis, W., Pass, H. I., Walther, M. M., and Linehan, W. M. Surgical management of pheochromocytoma with the use of metyrosine. Ann.Surg., 212: 621-628, 1990.

168. Pass, H. I., Tochner, Z., DeLaney, T., Smith, P., Friauf, W., Glatstein, E., and Travis, W. Intraoperative photodynamic therapy for malignant mesothelioma. Ann.Thorac.Surg., 50: 687-688, 1990.

169. Wall, R. T., Buzzanell, C. A., Epstein, T. A., Malech, H. L., Melnick, D., Pass, H. I., and Gallin, J. I. Anesthetic considerations in patients with chronic granulomatous disease. J Clin Anesth., 2: 306-311, 1990.

170. Robertson, C. N., Linehan, W. M., Pass, H. I., Gomella, L. G., Haas, G. P., Berman, A., Merino, M., and Rosenberg, S. A. Preparative cytoreductive surgery in patients with metastatic renal cell carcinoma treated with adoptive immunotherapy with interleukin-2 or interleukin-2 plus lymphokine activated killer cells. J Urol., 144: 614-617, 1990.

171. Perry, R. R., Matthews, W., Mitchell, J. B., Russo, A., Evans, S., and Pass, H. I. Sensitivity of different human lung cancer histologies to photodynamic therapy. Cancer Res., 50: 4272-4276, 1990.

172. Travis, W. D., Pittaluga, S., Lipschik, G. Y., Ognibene, F. P., Suffredini, A. F., Masur, H., Feuerstein, I., Kovacs, J., Pass, H. I., Condron, K. S., and . Atypical pathologic manifestations of Pneumocystis carinii pneumonia in the acquired immune deficiency syndrome. Review of 123 lung biopsies from 76 patients with emphasis on cysts, vascular invasion, vasculitis, and granulomas. Am.J Surg.Pathol., 14: 615-625, 1990.

173. Pass, H. I., Doppman, J. L., Nieman, L., Stovroff, M., Vetto, J., Norton, J. A., Travis, W., Chrousos, G. P., Oldfield, E. H., and Cutler, G. B., Jr. Management of the ectopic ACTH syndrome due to thoracic carcinoids. Ann.Thorac.Surg., 50: 52-57, 1990.

174. Perry, R. R., Venzon, D., Roth, J. A., and Pass, H. I. Survival after surgical resection for high-grade chest wall sarcomas. Ann.Thorac.Surg., 49: 363-368, 1990.

175. Feurestein, I. M., Archer, A., Pluda, J. M., Francis, P. S., Falloon, J., Masur, H., Pass, H. I., and Travis, W. D. Thin-walled cavities, cysts, and pneumothorax in Pneumocystis carinii pneumonia: further observations with histopathologic correlation. Radiology, 174: 697-702, 1990.

176. Evans, S., Matthews, W., Perry, R., Fraker, D., Norton, J., and Pass, H. I. Effect of photodynamic therapy on tumor necrosis factor production by murine macrophages. J Natl.Cancer Inst., 82: 34-39, 1990.

177. Pass, H. I. and Reed, C. E. Lasers in the management of upper aerodigestive malignancies. Important Adv.Oncol, 159-179, 1990.

178. Doppman, J. L., Pass, H. I., Nieman, L., Cutler, G. B., Jr., Chrousos, G. P., and Loriaux, D. L. Failure of bronchial lavage to detect elevated levels of adrenocorticotropin (ACTH) in patients with ACTH-producing bronchial carcinoids. J Clin Endocrinol.Metab, 69: 1302-1304, 1989.

179. Takahashi, T., Nau, M. M., Chiba, I., Birrer, M. J., Rosenberg, R. K., Vinocour, M., Levitt, M., Pass, H., Gazdar, A. F., and Minna, J. D. p53: a frequent target for genetic abnormalities in lung cancer. Science, 246: 491-494, 1989.

180. Horan, J. J., Robertson, C. N., Choyke, P. L., Frank, J. A., Miller, D. L., Pass, H. I., and Linehan, W. M. The detection of renal carcinoma extension into the renal vein and inferior vena cava: a prospective comparison of venacavography and magnetic resonance imaging. J Urol., 142: 943-947, 1989.

181. Matthews, W., Rizzoni, W., Mitchell, J., Russo, A., and Pass, H. In vitro photodynamic therapy of human lung cancer. J Surg.Res., 47: 276-281, 1989.

182. Doppman, J. L., Nieman, L., Miller, D. L., Pass, H. I., Chang, R., Cutler, G. B., Jr., Schaaf, M., Chrousos, G. P., Norton, J. A., Ziessman, H. A., and . Ectopic adrenocorticotropic hormone syndrome: localization studies in 28 patients. Radiology, 172: 115-124, 1989.

183. Perry, R. R., Rosenberg, R. K., and Pass, H. I. Tracheoesophageal fistula in the patient with lymphoma: case report and review of the literature. Surgery, 105: 770-777, 1989.

184. Rosengart, T. K., Pass, H., Cannon, R., Miller, D. L., Solomon, D., and Clark, R. E. Ruptured gastroepiploic artery aneurysm and vascular collapse in a patient with thoracic aneurysm. J Cardiovasc.Surg.(Torino), 30: 514-516, 1989.

185. Cook, J. A., Pass, H. I., Russo, A., Iype, S., and Mitchell, J. B. Use of monochlorobimane for glutathione measurements in hamster and human tumor cell lines. Int.J Radiat.Oncol Biol.Phys., 16 : 1321-1324, 1989.

186. Jablons, D., Steinberg, S. M., Roth, J., Pittaluga, S., Rosenberg, S. A., and Pass, H. I. Metastasectomy for soft tissue sarcoma. Further evidence for efficacy and prognostic indicators. J Thorac.Cardiovasc.Surg., 97: 695-705, 1989.

187. Pass, H. I., DeLaney, T., Smith, P. D., Bonner, R., and Russo, A. Bronchoscopic phototherapy at comparable dose rates: early results. Ann.Thorac.Surg., 47: 693-699, 1989.

188. Perry, R. R., Evans, S., Matthews, W., Rizzoni, W., Russo, A., and Pass, H. I. Potentiation of phototherapy cytotoxicity with light scattering media. J Surg.Res., 46: 386-390, 1989.

189. Matthews, W., Cook, J., Mitchell, J. B., Perry, R. R., Evans, S., and Pass, H. I. In vitro photodynamic therapy of human lung cancer: investigation of dose-rate effects. Cancer Res., 49: 1718-1721, 1989.

190. Rex, J. H., Ginsberg, A. M., Fries, L. F., Pass, H. I., and Kwon-Chung, K. J. Cunninghamella bertholletiae infection associated with deferoxamine therapy. Rev.Infect.Dis., 10: 1187-1194, 1988.

191. Lefor, A. T., Merino, M. M., Steinberg, S. M., Dwyer, A., Roth, J. A., Flanagan, M., and Pass, H. I. Computerized tomographic prediction of extraluminal spread and prognostic implications of lesion width in esophageal carcinoma. Cancer, 62: 1287-1292, 1988.

192. Sindelar, W. F., Hoekstra, H. J., Kinsella, T. J., Barnes, M., DeLuca, A. M., Tochner, Z., Pass, H. I., Kranda, K. C., and Terrill, R. E. Response of canine esophagus to intraoperative electron beam radiotherapy. Int.J Radiat.Oncol Biol.Phys., 15: 663-669, 1988.

193. Travis, W. D., Linnoila, R. I., Horowitz, M., Becker, R. L., Jr., Pass, H., Ozols, R., and Gazdar, A. Pulmonary nodules resembling bronchioloalveolar carcinoma in adolescent cancer patients. Mod.Pathol., 1: 372-377, 1988.

194. Roth, J. A., Pass, H. I., Flanagan, M. M., Graeber, G. M., Rosenberg, J. C., and Steinberg, S. Randomized clinical trial of preoperative and postoperative adjuvant chemotherapy with cisplatin, vindesine, and bleomycin for carcinoma of the esophagus. J Thorac.Cardiovasc.Surg., 96: 242-248, 1988.

195. Pogrebniak, H. W., Stovroff, M., Roth, J. A., and Pass, H. I. Resection of pulmonary metastases from malignant melanoma: results of a 16-year experience. Ann.Thorac.Surg., 46: 20-23, 1988.

196. Perry, R. R., Knego, R. S., and Pass, H. I. Trachea-innominate artery fistula. J Thorac.Cardiovasc.Surg., 96: 184-185, 1988.

197. Ognibene, F. P., Pass, H. I., Roth, J. A., Shelhamer, J. H., and Milne, E. N. Role of imaging and interventional techniques in the diagnosis of respiratory disease in the immunocompromised host. J Thorac.Imaging, 3: 1-20, 1988.

198. Wiebke, E. A., McDonald, H. D., and Pass, H. I. The infected chest wall prosthesis: management by excision and contralateral transverse rectus abdominis musculocutaneous flap. Ann.Thorac.Surg., 44: 544-545, 1987.

199. Lanza, L. A., Miser, J. S., Pass, H. I., and Roth, J. A. The role of resection in the treatment of pulmonary metastases from Ewing's sarcoma. J Thorac.Cardiovasc.Surg., 94: 181-187, 1987.

200. Pass, H. I., Sindelar, W. F., Kinsella, T. J., DeLuca, A. M., Barnes, M., Kurtzman, S., Hoekstra, H., Tochner, Z., Roth, J., and Glatstein, E. Delivery of intraoperative radiation therapy after pneumonectomy: experimental observations and early clinical results. Ann.Thorac.Surg., 44: 14-20, 1987.

201. Doppman, J. L., Loughlin, T., Miller, D. L., Pass, H. I., Chrousos, G. P., Cutler, G. B., Oldfield, E. H., and Loriaux, D. L. Identification of ACTH-producing intrathoracic tumors by measuring ACTH levels in aspirated specimens. Radiology, 163: 501-503, 1987.

202. Wall, R. T., Pass, H. I., and McDonald, H. D. Unusual presentation and novel solution for hemodynamic compromise during thoracic surgery. Anesthesiology, 66: 566-568, 1987.

203. Barnes, M., Pass, H., DeLuca, A., Tochner, Z., Potter, D., Terrill, R., Sindelar, W. F., and Kinsella, T. J. Response of the mediastinal and thoracic viscera of the dog to intraoperative radiation therapy (IORT). Int.J Radiat.Oncol Biol.Phys., 13: 371-378, 1987.

204. Rizzoni, W. E., Pass, H. I., Wesley, M. N., Rosenberg, S. A., and Roth, J. A. Resection of recurrent pulmonary metastases in patients with soft-tissue sarcomas. Arch.Surg., 121: 1248-1252, 1986.

205. Edington, H., Salwitz, J., Longo, D. L., Roth, J. A., and Pass, H. Thymic hyperplasia masquerading as recurrent Hodgkin's disease: case report and review of the literature. J Surg.Oncol, 33: 120-123, 1986.

206. Roth, J. A., Pass, H. I., Wesley, M. N., White, D., Putnam, J. B., and Seipp, C. Comparison of median sternotomy and thoracotomy for resection of pulmonary metastases in patients with adult soft-tissue sarcomas. Ann.Thorac.Surg., 42: 134-138, 1986.

207. Udelsman, R., Roth, J. A., Le