Mesothelioma Science News
San Pedro, CA - January 10, 2008
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Peritoneal mesothelioma: surgery and
intraperitoneal hyperthermic chemotherapy show promise
in selected patients in Israel
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Peritoneal mesothelioma survival improves with
surgery plus intraperitoneal chemotherapy in patients
in France
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Peritoneal mesothelioma survival increased with
surgery and intra-peritoneal hyperthermic chemotherapy
in selected patients in Italy
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EPP patients have highest percentage of major
complications, median survival of 16 months
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Carboplatin-pemextrexed chemotherapy in Italian
pleural mesothelioma yields 14-month median
survival
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New monoclonal antibody with an affinity for
human mesothelin may prevent adhesion of
mesothelin-bearing tumor cells and may elicit
cell-mediated cytotoxicity on mesothelin-bearing tumor
cells
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Combined PET-CT scanning is better for treatment
and therapy of pleural mesothelioma than CT scanning
alone
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Key peptide is an important marker for
mesothelioma in asbestos-exposed patients
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Independent factors of stage of disease,
histology type, time since diagnosis, pain, and
appetite loss may be prognostic factors in patients
with advanced MPM
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Study of 397 patients shows significant
predictors of survival include performance status,
platelet count, histology, and degree of involvement of
pleural cavity rather than multimodality
therapy
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Podoplanin a better immunohistochemical marker
for sarcomatoid mesothelioma than calretinin
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Pleuropneumonectomy not required for rare cases
of localized (as opposed to diffuse) pleural
mesothelioma
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Low exposure to chrysotile causes production of
cytokines that lead to development of fibers in
lungs
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Environmental exposure to waste asbestos causes
pleural mesothelioma
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Asbestos industry's smear campaign against
advocate who exposed their cover-up of asbestos
dangers
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Tumor growth in long and short-term pleural
mesothelioma survivors affected by certain
proteins
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U.S. incidence of mesothelioma is 1.1 cases per
100,000 people
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High rates of mesothelioma among women and girls
exposed to asbestos in Western Australia
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Environmental sampling in city of Thetford Mines
indicates serious asbestos threat to public
health
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Risk model being developed to predict lung cancer
and mesothelioma
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Counting techniques undercount the presence of
chrysotile when monitoring airborne fibers
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