Mesothelioma Science News September 23, 2008

Mesothelioma Science News
San Pedro, CA - September 23, 2008

Radiation therapy
A review of intensity-modulated radiation therapy Click here

Meso support networks
Hands of Time: the experience of establishing a support group for people affected by mesothelioma Click here

Patient survival
Survival of peritoneal malignant mesothelioma in Italy: A population-based study Click here

Meso staging
Computed tomography, positron emission tomography, positron emission tomography/computed tomography, and magnetic resonance imaging for staging of limited pleural mesothelioma: initial results Click here

Preoperative staging of mesothelioma by 18F-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography fused imaging and mediastinoscopy compared to pathological findings after extrapleural pneumonectomy Click here

Diagnosis
Metastasis of malignant peritoneal epithelioid mesothelioma in endoscopic gastric biopsy: A diagnostic pitfall Click here

Cellular research
Proteasome inhibitor MG132 induces apoptosis and inhibits invasion of human malignant pleural mesothelioma cells Click here

Peritoneal meso
Peritoneal mesotheliomas: clinicopathologic features, CT findings, and differential diagnosis Click here

Chrysotile
Orally ingested chrysotile asbestos affects rat lungs and pleura Click here


We Salute

Bob Treggett

Almost five years since Bob Treggett was diagnosed with malignant pleural mesothelioma, this powerful and gentle man succumbed to asbestos cancer on August 23, 2008. A full three years after undergoing an EPP with Dr. Eric Vallieres, Bob had already beaten the average survival time for an illness that typically claims its victims in seven months. Bob continued on to enjoy life and give of life as he battled with a refractory and tenacious tumor.

Bob TreggettCheerfully grappling with the loss of mobility that accompanies a surgery like the EPP, Bob embarked on missionary work that took him to South Africa, Kenya, India, and the Philippines. He saw each day as a gift and spent every hour marveling at the good fortune of being surrounded by a loving family.

Able to sit and talk for hours, Bob found few things as gratifying as his ministry. "God has trained me to travel overseas to train pastors and church leaders," he once said in preparation for his missionary work.

A submariner on the nuclear sub USS John Marshall, Bob found time after his diagnosis to advocate for federal funding and for an asbestos ban. "It's never too late to do the right thing," Bob was fond of saying when discussing the government's obligation to ban the poison and to invest in research that will prevent and treat those afflicted with asbestos cancer. Bob's strength, decency, and moral courage will be sorely missed by us all.

Sharon Johnson

Nine years of struggle, triumph, and courage ended for Sharon Johnson on September 11, 2008, when she finally set down arms in her own personal battle against malignant peritoneal mesothelioma. Sharon's two sisters were also victims of mesothelioma, both pleural and peritoneal. Her sister Sue continues to successfully battle the disease.

Sharon JohnsonSharon's surgery with Dr. Robert Taub and Dr. John Chabot, and her good fortune in detecting the cancer early, resulted in effective treatment that produced results far beyond what most mesothelioma patients experience. However, Sharon's experience also highlights what many in the mesothelioma community have recognized: pleural and peritoneal mesothelioma are very different diseases from the standpoint of treatment and survival, even though they are both cancers of the mesothelial lining. In addition to conventional therapy, Sharon also treated at the IAT clinic in the Bahamas.

Sharon's valiant battle and her success in outlasting the odds point again to the crucial need for asbestos research funding that will address these diseases in a systematic way, pinpointing prevention and treatment strategies, and putting resources into understanding why two similar asbestos cancers have such different prognoses.

Our thoughts are with Sharon's family. She has been a shining example to all who knew her.

Bottom of the Ninth

Congress will soon decide whether the bill to ban asbestos will be sent to mark-up, a committee vote, and on to the House for a full vote. You can do a huge part by visiting ADAO's www.banasbestos.us or the MARF online action center to send a message to your senators and representative, letting them know that you support HR 6309's goal of banning asbestos and funding for meso research.

Got Data?

Lawyers donate money to mesothelioma research, but in the course of representing a client, they also generate vast amounts of medical records. Some attorneys have estimated that the mere cost for accessing a client's medical records in a mesothelioma case can exceed $7,000.

Unfortunately, after a case closes, those records sit in a file storage room or reside tucked away on a server where they serve no useful purpose ever again. For the last couple of years, the Pacific Heart, Lung & Blood Institute has been working on a clinical database project that will turn those mountains of records into razor sharp weaponry in the war on meso.

At the upcoming IMIG Congress in Amsterdam our firm will propose anonymously donating records with the client/patient's approval to a clinical mesothelioma database project. Cancer databases for other tumors have been successfully implemented, and the sheer number of records aggregated by lawyers could quickly build an enormous data fund from which doctors and scientists could learn more, and learn quickly, about meso.

Such a global clinical database would also allow patients to upload medical records from their home computer, and it would also provide doctors and labs the ability to upload data. The critical mass created by this project could identify trends, treatments, and research areas that might ultimately remove the isolation and orphan status associated with mesothelioma.