Immunotherapy and Interleukin
Interleukin is a biological response modifier (substance that can improve the body's natural response to infection and disease) that helps the immune system fight infection and cancer. These substances are normally produced by the body. They are also made in the laboratory for use in treating cancer and other diseases.
Additional Information
Conclusions: The chimeric protein, IL-4(38-37)-PE38KDEL, has potent antitumor effects against MPM both in vitro and in vivo. More...
Combined Epirubicin and Interleukin-2 Regimen in the Treatment of MM: A Multicenter Phase II Study of the Italian Group on Rare Tumors (8/29/00)
The Italian Group on Rare Tumors undertook a phase II study of a combination of epirubicin and interleukin-2 in 21 chemotherapy-naive patients with malignant mesothelioma. All patients had bidimensionally measurable disease at CT scan. More...
Experimental Protocol: Immunization against Cancer Cells using Interleukin-2 and Macrophage Colony Stimulating Factor, Mike McCoy, Ph.D.
Mike McCoy was formerly employed at the National Cancer Institute as a Staff Immunologist. You might want to review the Primer above to better understand the medical jargon and the goals and mechanisms of immunotherapy.
The title of the protocol is "Experimental Protocol for Immunization of Cancer Patients with Immunotherapy Treatment Containing Tumor Associated Antigens Formulated with Low Doses of Interleukin-2 and Granulocyte Macrophage Colony Stimulating Factor." More...
Australia Doctors: Gene Therapy (IL-12) Retards Mesothelioma in Mice But Causes Side Effects (9/27/99)
Gene therapy that boosts the body's immune system appears to be effective at preventing mesothelioma -- a lethal tumor of the lining of the chest -- from growing in mice, according to Australian researchers. More...