Mesothelioma Empowerment Update - May 10, 2012

Click here for Empowerment Archives!

"Virtually indestructible" 71-year Old Retired Painter Tells Mesothelioma "Go away, I don't have time for you," Erin, TN

In February of 2011, John Elliot went to see his family physician in Erin, Tennessee, complaining of a constant stomach ache and being unusually tired. You see, John's primary hobby and most favorite thing to do every day was - work. He has worked as a painter since the early 1960s when he taught himself the ins and outs of house painting.

His first job was for an elderly couple who gave him a $50 bonus for a job well done. John says that with the extra money, he almost broke even on the job. That simple bonus showed him that hard work and attention to detail pays off in the end. More...


68 Year-Old Malignant Mesothelioma Survivor Taking It One Day at a Time. Enumclaw, WA

Bonnie Von Dell is a wife, a mother of two, a grandma of three and a mesothelioma survivor. Born in a car as her mother was driving from Minnesota to Washington to find work while Bonnie's father was serving in WW2, Bonnie has travelled a long hard road.

Bonnie had experienced recurrent bouts of pneumonia and believed she had developed an infection when she began feeling chest pain and shortness of breath in the fall of 2009. X-rays confirmed she had a pleural effusion and a possible mass in her left lung.. More...


73 Year-Old Retired Helicopter Pilot and Vietnam Vet Beats Peritoneal Mesothelioma, Twice. De Ridder, LA

Tom Bradford is an engaging, funny native East Texan with a bright outlook. He and his wife Patricia have been married for 52 years, have three adult children and a couple of grandkids. He has always been an adventurer, a lover of motorcycles (he has four in his garage) and he loves traveling around the country on the back of one.

Tom was enlisted in the U.S. Army from 1958 to 1961. In 1962, he was getting disappointed at his job opportunities and he had enjoyed his time in the military so he decided to make a career out of it. He re-enlisted and served in Vietnam and all over the world as a cryptograph technician, a helicopter pilot, mechanic, instructor and supervisor until retiring from the Army in 1981. More...


Roger and Ann Worthington Donate $25,000 to Amgen's Breakaway from Cancer Walk in Dana Point, California

LOS ANGELES, May 8, 2012 /PRNewswire via COMTEX/ -- Roger and Ann Worthington, longtime supporters of mesothelioma patients and their families, generously donated $25,000 to The Pacific Meso Center(PMC). "Their donation honors the mesothelioma patients and their families who joined other cancer survivors in the Amgen Breakaway from Cancer Walk at the Dana Point Grand Prix of Cycling on Sunday, May 6th 2012," said Clare Cameron, executive director of PMC. The walk took place at 3:35 p.m. prior to the professional men's race. More...



Walking the Walk at the Amgen Dana Point Grand Prix 

Meso-Byte date, Monday, May 7, 2012

On Sunday, May 6, 2012, bike racers, kids, and anti-cancer advocates"occupied" downtown Dana Point, California at the 6th Annual Dana Point Grand Prix of Cycling. With almost 1000 racers and twelve races going from 7:00 a.m. to 6:00 p.m., the DPGP is the biggest single-day cycling event in the country and it continues to grow every year.

The delight of the day for me was the kids' race; about 400 kids of all ages, from tiny to tall, pedaling their little legs off. I'm still smiling and laughing about it.  More...


Worthington Law Firm to Support 2nd International Symposium on Lung-Sparing Therapies for Mesothelioma

Meso-Byte date, Monday, April 16, 2012

Mesothelioma experts will gather on Saturday, May 12th 2012 at the Sheraton Delfina Hotel in Santa Monica, California for the 2nd Annual International Symposium on Lung-Sparing Therapies for Malignant Pleural Mesothelioma. Dr. Robert Cameron, Director of the UCLA Mesothelioma Comprehensive Research Program and Chief of Thoracic Surgery at the West Los Angeles VA Medical Center, will lead the symposium again this year. Dr. Cameron has been a leading proponent of the lung-sparing pleurectomy/decortication surgical procedure for nearly 20 years.

The distinguished faculty at this year's meeting will include experts from Houston, San Francisco, New York and as far away as South Africa, with additional experts in a wide range of medical/scientific fields. More...


Brett Clare Powers Break Away to Victory: "Love ya Dad!" 

Meso-Byte date, Monday, March 12, 2012

Murietta, CA. Brett Clare works hard, trains hard, and plays hard. But when it comes to cancer survivors, he's understandably got a soft spot

"I'm dedicating this win to my Dad," Brett beamed, moments after winning the Tour of Murietta Criterium. "I know it sounds cliché but I wish my Dad could've been here to see it."

Brett races for Breakaway from Cancer, the masters bicycling team co-sponsored by the Pacific Meso Center, a non-profit dedicated to converting fatal asbestos-caused lung cancer into a chronic and survivable diseases. Breakaway from Cancer is an initiative of the biotech giant Amgen, Inc., which applauds PMC's clinical interest in immunotherapy. Three members of the BFC team have lost their Dads to asbestos cancer.  More...


 

Diagnosis/Staging:

A Combination of Biomarkers Improves the Diagnosis of Mesothelioma in Pleural Effusions (5/2012)

The combination of SMRP/CCL2/galectin-3 seems to represent a promising panel of biomarkers for the reliable diagnosis of MPM in pleural fluid  More...

Activated Leukocyte Cell-Adhesion Molecule (ALCAM) Promotes Malignant Phenotypes of Mesothelioma (5/2012)

Study suggests that overexpression of ALCAM contributes to tumor progression in mesothelioma and that ALCAM might be a potential therapeutic target of mesothelioma.  More...

Protein Identified as Critical Link in Development of Mesothelioma (4/16/2012)

Researchers at University of Hawaii have identified a protein known as HMGB1 as a critical link in the development of mesothelioma. The new study outlines the specific role HMGB1 plays in the growth and development of mesothelioma  More... 

Age of Exposure May Predict Future Mesothelioma Diagnosis (11/10/2011)

Study in the European Respiratory Journal showed that older workers had less of a chance of developing mesothelioma than their younger counterparts. More...

Surgery & Multimodal Treatment:

Radical Pleurectomy and Intraoperative Photodynamic Therapy for Mesothelioma (5/2012)

Study's results showed it was possible to achieve a macroscopic complete resection using lung-sparing surgery in 97% of patient group with stage III/IV disease. It concludes that the results of this lung-sparing approach are safe and encouraging. More... 

Prospective Study on Functional Results After Lung-Sparing Radical Pleurectomy (5/2012)

Lung-sparing Radical pleurectomy leads to significant improvement of pulmonary function and perfusion after a recovery time of 2 months. Functional results are better after preservation of the diaphragm. Preservation of physiological reserve via lung-sparing Radical pleurectomy might allow patients with MPM to be eligible for further therapeutic options in the long term. More...

Pleurectomy/Decortication is Superior to Extrapleural Pneumonectomy in the Multimodality Management of Patients with Malignant Pleural Mesothelioma (4/2012)

Dr. Lang-Lazdunski's study finds that P/D, hyperthermic pleural lavage with povidone-iodine and adjuvant chemotherapy were superior to neoadjuvant chemotherapy, EPP and adjuvant radiotherapy. More...

Is it Time to Consider Pleurectomy and Decortication as the Only Surgical Treatment for Malignant Pleural Mesothelioma? (4/2012)

Peer-review of Dr. Lang-Lazdunski's study on P/D concludes that it provides additional data that should lead us to consider P/D in all trials of treatment for mesothelioma. However, it is too early based on this data to completely abandon EPP altogether. More... 

Chemotherapy: 

Zoledronic Acid Produces Antitumor Effects on Mesothelioma (5/2012)

Study indicates that zoledronic acid induces apoptosis or S-phase arrest and suggest that it is a possible therapeutic agent to mesothelioma. More...

SOCS-1 Gene Delivery Cooperates with Cisplatin Plus Pemetrexed to Exhibit Preclinical Antitumor Activity Against Malignant Pleural Mesothelioma.(4/24/2012)

SOCS-1 gene delivery has a potent antitumor effect against MPM and a potential for clinical use in combination with cisplatin plus pemetrexed  More... 

Novel and Alternative Treatments:

Flavonoid Resveratrol Found in Red Wine Suppressed Growth of Mesothelioma Cells (4/23/2012)

Study strongly suggests that resveratrol targets human mesothelioma cells by inhibiting Sp1 protein levels  More... 

The Circadian Clock Gene BMAL1 is a Novel Therapeutic Target for Malignant Pleural Mesothelioma (4/17/2012)

Findings indicate that BMAL1 has a critical role in MPM and could serve as an attractive therapeutic target for MPM.  More... 

Firefly Glow Guides Surgeons to Successful Removal of Mesothelioma Cells (3/2/2011)

Bioluminescence can assess and guide thermal treatment of mesothelioma. This encourages research into bioluminescence imaging as a molecular technique with potential to target tumors via biomarkers and optimize thermal treatment procedures in a clinical setting. More..

Palliative Care:

Cachexia (muscle/weight loss)-cancer's Companion Condition (2/27/2012)

Cachexia has a detrimental effect on quality of life and is especially prevalent in pancreatic and lung cancers since those patients also tend to lose their appetites. Two potential cachexia treatments are now in Phase 3 clinical trials. If studies continue to go well, the drugs could become available for lung cancer patients within the next two to three years. The main goal of both medications is to give people more muscle strength as they fight cancer. More...

Palliative Care in the Management of Lung Cancer Should be a Priority (1/2012)

Many individuals with lung cancer perceive pain from both their disease and their cancer treatment. However, some study respondents did not use analgesics due to concerns of addiction, cost, or their healthcare providers not recommending analgesics. Medical professionals providing medical management for lung cancer patients should make pain management a priority and regularly discuss pain symptoms and pain management with patients.  More...